Pathophysiology Definitions And Key Terms

Absorption ? – gets the drug into the bloodstream via dermal layers, mouth, subcutaneous tissue, muscle, or lining of stomach. Adverse Reactions? – Undesirable side effects of a drug Aerosol? – Liquid, powder, or foam deposited in a thin layer of the skin by air pressure. American Hospital Formulary Service? – Contains concise information that is arranged according to drug classifications. Ampule? – Glass container containing a drug, the bottle must be broken at the neck to retrieve the medication.

Anaphylactic Reaction? – Life threatening reaction resulting in respiratory distress, sudden severe bronchospasms and CV collapse. Antagonist? – Drug that prevents receptor stimulation. Blocks receptors and therefore blocking action of toxic drugs. Apothecary System? – System for measuring drug dosages. Gradually being replaced by metric. Chemical Name? – The 1st name given to any drug. Gives the exact description of the chemical structure of the drug. Compendium of Drug Therapy?

– Includes pictures of drugs and phone numbers of drug companies and poison control centers. Contraindications? – reasons NOT to administer meds Controlled Substances Act? – Regulates manufacture and distribution of drugs whose use may result in dependency. Cumulative Effect? – the effect of multiple doses of a drug interacting with each other Distribution?

– Moves drug from bloodstream into the tissues and fluids of the body Drug? – Any substance taken into the body to affect changes to 1 or more body functions, often to prevent or treat a condition. Drug Action? – Cellular changed effected by a drug Drug Allergy? – occurs in a person who has been exposed to the drug and developed antibodies. Drug Effect? – Degree of a drug’s physiologic change Drug Enforcement Administration? – Oversees control of dangerous drugs. Enforces drug laws.

Drug Tolerance? – when body becomes accustomed to a drug over a period of time. Results in decreased effect of same dosage. Drug Toxicity? – results from overdosage, ingestion of a drug intended for external use or buildup of the drug in blood due to impaired metabolism. Elixir? – Drug dissolved in alcohol and added flavoring. DONT USE in pts with alcoholism or diabetes. Emulsion? – Drug combined with water and oi. Must be thoroughly shaken to disperse meds evenly Enteric-Coated Tablet? – Drug coated to withstand stomach acidity and dissolve in the intestines. Never to be crushed or broken.

Excretion? – Eliminates the waste products of drug metabolism from the body Federal Food, Drug, and Cosmetic Act? – Required that the safety of a drug must be proven before it could be distributed to the public. Federal Trade Commission? – Regulates drug advertising Fight or Flight? – The reaction activated by the sympathetic nervous system as a response to external life threatening stimuli Fluid Extract? – Alcohol solution of a drug from vegitable source. Most concentrated of all fluid preperations. Food and Drug Administration? – reviews drug applications and petitions for food additives.

Inspects factories and insures labeling on cosmetics. Generic Name? – Often related to the chemical name but completely independent of the manufacturer’ nonproprietary designation of the drug Harrison Narcotic Act of 1914? – 1st legislation designed to s top drug addiction. Established food controls import and sale of opium. Hypersensitivity? – AKA drug allergy. Body must build this response. The 1st exposure may or may not indicate that a problem is developing. Idiosycratic Reactions? – Abnormal reaction to drug peculiar to a certain patient. Not technically an allergy. Indications?

– reasons for the administration of drugs Inhalation? – administration of drugs into the lungs via water vapor, gases or drug inspiration Intramuscular? – administration of drugs via injection into muscle Intraosseous? – administration of drugs directly into the bone. OUCH. Intravenous? – administration of drugs via injection directly into veins Liniment? – Any oily liquid used on skin Local Effect? – limited to the area where it is administered Metabolism? – Physical and chemical alterations t hat the drug undergoes within the body Metric System? – based on multiples of 10, used to measure dosages.

Always in decimals; never in fractions Narcotic Control Act? – Passed to ammend Harrison act and increase penalties for violation. Made possession of heroin and pot illegal. Official Name ? – The name under which a drug is listed in one of the official publications. Parasympathetic Division? – also called cholinergic, originates in brain and sends messages to affect organs by the cranial nerves Parenteral Drugs? – Liquid drugs administered into the body by subcutaneous, intramuscular or intravenous routes. Pharmacokinetics? – Movement of drugs through the body including absorption, distribution,

metabolism and excretion. Pharmacology? – The study of drugs and their effects and actions on the body Physicians’ Desk Reference? – Annually released reference for all drugs in current use Potentiation? – One drug prolongs or multiplies the effect of another drug Prefilled Syringe? – Syrings and drug solution packaged together. to be used to deliver a single dose of a drug. Public Health Service? – Inspects and licenses establishments that manufacture drugs Pure Food and Drug Act? – Passed in 1906 and ammended in 1938. Original act to prevent trafficking of harmful food and drugs. Side Effect?

– any drug effect that is unintended Subcutaneous? – Administration of drugs injected into fatty layer of tissue below the skin Sublingual? – Administration of drugs by placing it under the tongue to be dissolved into the saliva. MUST not be swallowed. Suppository? – Drug mixed in a firm base that dissolves gradually at body temperature. Shaped for insertion into the business end. Suspension? – Finely ground drugs dissolved in a liquid. Must be shaken before administration. Sympathetic Division? – AKA adreg Synergism? – Two drugs working together that enhance the desired effect Systemic Effect?

– Pertaining to the whole body rather than to one of its parts Therapeutic Effect? – Drug’s desired effect and the reason it is prescribed. Trade Name? – The name registered by the patent office for a given drug. Manufacturer for 17 years has exclusive rights of production. Transdermal? – drug delivered by absorption through the skin via patch United States Pharmacopeia? – Consists of 2 paperback volumes of drug information for the healthcare provider. Provides directions for compounding. Vials? – Glass or plastic containers that have a self-sealing rubber stopper from which multiple doses may be drawn.

Pathophysiology Definitions and Key Terms Absorption – gets the drug into the bloodstream via dermal layers, mouth, subcutaneous tissue, muscle, or lining of stomach. Adverse Reactions – Undesirable side effects of a drug Aerosol – Liquid, powder, or foam deposited …

The manner a drug enters the body is referred to as the route of administration. There are many different routes than can be utilized. The routes are: orally, otically, nasally, transdermal, rectally, vaginally; or injected through the skin in several …

Canadian Drug Legislation: Food and Drugs Act & regulation ? Health Canada ? Health Canada Products & Food branch ? Classification of therapeutics: Drugs (therapeutic products) Traditional drugs (chemical agents): Pills and tablets etc… Biologics & Genetic therapies Antibodies, Hormones …

The main components of pharmacology in substance use disorders include understanding how the methods of administration and routes of absorption affect the high in individuals. There is undeniably a chemical side to addiction. If a person consumes a substance, it …

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