The condition diphtheria, pertussis and tetanus are diseases caused by a bacterium microorganism, which is evidently counteracted by the means of DPT (diphtheria, pertussis and tetanus) vaccination. DPT vaccine is one of the most lifesaving and potent discovery that ever occurred in the history. The historical background in terms of the development of such vaccine has faced various research and studies, and with such delays, the global infection has gained its arousal.
As known to historical events, DPT vaccine has been utilized to cure the epidemic of diphtheria, and provide resistance to the said three conditions. The pathological concept of DPT involves mainly the pathogens themselves, which are inactivated through different genetic and microbial procedures. DPT vaccine does not provide an absolute resistance to the diseases at one given shot, but it requires several doses in accordance to the prescribed timeframe. Moreover, DPT does not directly cure the diseases involved but rather enhances the immunity of the individual if in case the diseases are encountered.
Nevertheless, even with beneficial and substantial contributions to the community both in local and international settings, DPT vaccine is still being criticized due to the reported and claimed side-effect related to the vaccine instillation. However, with all these claims and reports, the federal governments are still instilling the use of the vaccine; since, the reported negative cases are temporary while the advantages obtained from the vaccine can lasts a lifetime if doses prescribed are met. Scopes and Limitations
The primary target population of this research involves the head of the families, academic students and health care providers. In this study, we shall deal specifically to DPT vaccine in terms of its historical background and development, physiology and vaccination information involved, and the issues implicated in the use of such vaccine. We shall collate and integrate all the data gathered in a form of review of related literature. After which, we shall employ analysis on this paper and provide interpretations of data acquired.
Lastly, the compiled analysis, data inferences and data interpretations shall be used in comparison to the personal ideations and perspectives concerning the issue proposed. The following shall be the primary objectives of the study, which serves also as the research guidelines and protocols. A. To be able to define, elaborate and integrate the current subject, DPT, via data gathering of historical perspective, vaccine processes involved, and issues proposed B. To be able to provide critical analysis, data interpretation and body of integrative discussion on the gathered data acquired in DPT Purpose of the Study
The purpose of the study involves primarily the awareness expansion on the topic proposed, which is DPT. Significantly, the research can further clarify the issues presenting the utilization of DPT vaccine, especially in correlation with the vaccine’s side effects. Moreover, through the critical analysis and data management employed in the research, anxiety of the population in terms of the DPT vaccination can be reduced. Review of Related Literature Brief Disease Overview The diphtheria component of DPT vaccine is composed of inactivated diphtheria toxin adsorbed to aluminum salts (Merson, 2004 p.147).
Infection with Corynebacterium diphteriae-an aerobic, pleomorphic, gram-positive-rod- may lead to cardiac and neurologic disturbances due to toxin production of the bacterium itself. The disease is preventable by vaccination with inactivated C. diphtheriae toxin or toxoid. Humans are the only known reservoir for C. diphtheriae, and most persons are asymptomatic carriers of the organism. The organism spreads from person to person in respiratory droplets or oral secretions. Diphtheria usually begins with fever, sore throat, and malaise.
The dirty gray membrane usually develops first on the tonsils and may spread throughout the posterior oropharynx. The membrane is firmly adherent, and an attempt to strip it from the underlying mucosa initiates bleeding. Cardiac and neurologic symptoms develop in a minority of infected persons, usually those with the most severe local disease. In the past, diphtheria was a leading cause of death in children 2 to 15 years of age, but in Western countries, immunization programs have largely eliminated the disease. However, diphtheria persists as a major health problem in less-developed countries (Rubin & Strayer, 2007 p. 308).