Immune system

John Snow’s approach to explaining cholera and how it spread consisted primarily of morbid poison entering the alimentary canal through means of contaminated water consumption. Snow believed this to be the basis of how cholera was contracted by individuals and believed improper sewage filtration was to blame as well as a means of spreading the disease from person to person. However, previous explanations of how cholera was contracted consisted of the theory of airborne infection. This theory proposed that cholera was contracted by inhaling air at low levels of altitude by such people as workers in slaughterhouses and bone merchants.

This theory also proposed that the foul-smelling odors associated with these occupations were closely correlated with transmission. Having had previous knowledge of respiratory physiology, Snow dismissed the idea of cholera spreading by means of airborne infection because it had no relevance of what he already knew of inhalant anesthetics. Snow backed up his position by pointing out that if inhaling air in a workplace such as a slaughterhouse were the means in which the transmission of cholera occurred, then the workers in them would be primary targets in contracting the disease.

Since this was not the case, Snow continued to stick with his theory of cholera being transmitted by swallowing “morbid matter” specific to the disease. (Snow) Snow further attempted to prove his theory of waterborne transmission of cholera by conducting studies in various London sub districts in August of 1848. In this study he found that homes whose water was supplied to them by the Lambeth Water Company had few incidents of cholera, whereas homes whose water was supplied to them by the Southwark and Vauxhall Water Company had high incidences of cholera.

Snow concluded that the reasons for various cholera incidents involving different water companies had to do with where the companies drew their water supply. Snow believed Lambeth Water Company customers had few incidents with cholera because their water came from the upper reaches of the Thames River (“water free from heavy fecal contamination of the lower reaches of the Thames”), whereas Southwark and Vauxhall Water Company had high incidences of cholera because their water came from the lower reaches of the Thames River (water with heavy fecal contamination).

(Snow) Although this study shows strong correlation involving contaminated fecal water and cholera, people were still hesitant in believing Snow’s theory of cholera victims becoming infected by swallowing other people’s fecal matter. Thus, most people continued to support the airborne infection theory. In what would later in time be acknowledged by society as strong convincing evidence in support of Snow’s theory of cholera; Snow yet again conducted a study in which he correlated mortality with the source of water.

This time his study was far less vague than his previous study and accurately linked the outbreak of cholera in Golden Square to the water pump on Broad Street. Snow went about conducting his study by interviewing all the residents of Broad Street; the majority of which complained of smelling an unpleasant odor coming from the water pump on Broad Street. Based on interview complaints alone, Snow then sought out statistics concerning cholera deaths in the Soho area. The results Snow found correlated strongly with his initial belief of how cholera was spread.

These results indicated that the majority of cholera deaths occurred in the vicinity of the Broad Street water pump. Although Snow’s findings initially provoked the board of governors of the local St. James Parish to remove the Broad Street pump handle, the medical board of London were not entirely convinced and ordered the pump handle to be replaced. Although Snow was never able to convince his peers early on of his theory that ingestion of contaminated water was the cause of cholera, he did recommend actions that could be taken in the presence of cholera and for preventing the disease from spreading.

These actions Snow provides in his pamphlet, “On the Mode of Communication of Cholera” consists of twelve measures society can perform in the presence of cholera and in preventing cholera and other diseases that are communicable in the same manner from spreading. The basis of the measures Snow suggests are strict cleanliness when dealing with sick individuals, proper preparations and filtration of water, and isolation between individuals that are sick and those who are not.

Snow’s measure of strict cleanliness consisted of people exhibiting proper hygiene skills when dealing with disease stricken individuals by means of correct hand washing techniques, proper disposal of infected garments, and appropriate means of food handling. Snow was also an advocate of correct means of water filtration, primarily based on his theory of how cholera was transmitted. Actions that Snow suggested concerning water preparations and filtration included such things as boiling water before consumption, better source locations established by water companies, and a more efficient sewage and filtration system be established.

When dealing with isolation between individuals that are sick and those who are not, Snow suggested such actions as monitoring those who are infected with cholera, simple separation between individuals living together that are and are not infected with cholera, and disguising the communicability of cholera from people because of the fact that knowledge of communicability concerning cholera would cause a panic among society.

Snow believed that by people exhibiting his suggestive actions concerning cholera, not only would the risk of transmitting cholera be greatly reduced, but people could become better educated with dealing with cholera as well. One of the most important aspects Snow utilized in developing his theory on cholera was the disease agent involved in cholera itself. This disease agent is known as typhoid fever and occurs when water is contaminated. Typhoid fever can develop when unsanitary sediments mixes with water in wells, pipes, and sewage systems.

By an individual accidentally swallowing the contaminated water, he or she would then have been exposed to cholera shortly after. If consumed, the typhoid fever will attack the small intestines and cause ulcerations. One of the things that is most notable about the disease agent in cholera is how it incubates in the body. This period of incubation is shorter than other epidemics or communicable diseases, in that the period of incubation for cholera is only one to two days long. This in terms allows for cholera to release morbid poison in the body and spread rapidly with little warning.

From Snow’s study on the disease agent in cholera, he was able (in his opinion) to disprove the theory of airborne infection. This was simply because of the mechanism in which the disease agent operates. By the disease agent having to be swallowed and ingested, Snow was led to believe that airborne infection simple did not correlate with the disease of cholera. I believe John Snow’s recognition of statistics seem to aid in his recognition of how cholera was spread and the means in which it is derived from. By gathering information on infected people’s locations, Snow was able to apply the knowledge gathered and relate it with cholera.

Mapping also played a major role in Snow’s findings on the disease as well. Utilization of maps helped Snow in presenting his theory on a more accurate level and could be used as evidence of Snow’s findings. In a sense, Snow’s maps not only showed locations of people that were infected with cholera, but it also acted as a means of further prevention. Because of Snow’s influences on the disease cholera, people after him are now aware of the disease agent in cholera and the means in which cholera is transmitted. His contribution to not only epidemiology, but also society as a whole should not be overlooked by anyone.

Made up of one cell They have the power to divide, can multiply on their own Exists everywhere but majority are completely harmless Viruses: Too small to be seen by the naked eye They can’t multiply on their own Viruses …

Communicable diseases are illnesses that can be transmitted from one person to another. Some of the examples include; Gonorrhea Tuberculosis Malaria Meningitis Transmission is the passing of communicable diseases from an infected host individual or a con- specific (belonging to …

Communicable diseases are illnesses that can be transmitted from one person to another. Some of the examples include; Gonorrhea Tuberculosis Malaria Meningitis Transmission is the passing of communicable diseases from an infected host individual or a con- specific (belonging to …

Communicable diseases are illnesses that can be transmitted from one person to another. Some of the examples include; Gonorrhea Tuberculosis Malaria Meningitis Transmission is the passing of communicable diseases from an infected host individual or a con- specific (belonging to …

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