Due to the few symptoms posed by the virus, it proves hard for the detection of the disease. In addition, the symptoms tend to reactivate without any symptoms. The easy way will also be through the growing of the viruses through cultures at the laboratories. The cultures will be derived from urine samples, throat swabs and bronchial lavages. For instance the persons suffering from HCMV when tested for hepatitis they prove to be negative though they show signs for the hepatitis. They should be tested for hepatitis A, B, and C.
These tests should be done now HCMV has been suspected and it should be done on the blood samples that need to be taken within a two-week period after suspicion. There is also the ELISA test that is used to be able to measure antibody to CMV through serological testing. This test is also used to tell the degree of the infection and the further it has gone in affecting the body organs of the patient. Treatment of CMV by antibiotics There is no drug for treating CMV. However, many researchers are still trying to find the vaccine that will help in alleviation of CMV.
Therefore, the first thing in the control of CMV the doctor needs to do some tests on the patient. The tests are mostly on the patient’s urine and throat swabs to check whether one is suffering from the disease. Research done on the disease did show that the reaction of the disease to antibiotics did not give fulfilling results. Taking for instance Antimicrob J. C. , (1991) together with the research department of microbiology at the University of Western Australia, Nedlands showed that:
“Nineteen antibiotics were screened for their effects on the proliferation of murine spleen cells in vitro. Ketoconazole suppressed lymphoproliferation at clinically attainable concentrations, whilst tetracycline, cephalothin, rifampicin, and ciprofloxacin were also inhibitory at relatively low concentrations. These antibiotics were selected for further study. High concentrations of cephalothin inhibited macrophage uptake of colloidal gold, while spleen cells from mice treated with ketoconazole responded poorly to mitogenic stimulation in vitro.
Humoral responses to ovalbumin, polyvinylpyrrolidone, and murine cytomegalovirus (MCMV) were not suppressed by oral administration of ketoconazole, tetracycline, cephalothin, rifampicin, or ciprofloxacin to mice. However, MCMV-infected mice receiving these antibiotics had increased virus loads and a greater persistence of virus and interstitial pneumonitis in their lungs. This was observed with clinically attainable serum concentrations of cephalothin, tetracycline, and ciprofloxacin.
The findings warrant further investigation as the antibiotics are used to control secondary infections in immunosuppressed patients, many of whom experience cytomegalovirus disease. ” The pretreatment shown in mice by the murine CMV, showed that it protected the mice from the lethal effects of the virus. This is due to the 50% increase lethal doses administered and a relevant decreasing in titers of infectious viruses thus replicated in the liver and the spleen. Prevention of CMV This disease is most common in the many communities in the world.
Moreover, the main mode of prevention of the disease ids by being able to take care of the health and hygiene of the people suffering from the disease. The simplest modes of prevention is through the cleanliness i. e. washing the hands after visiting the lavatories with water and soap, and desist from the use of touching fluids emitted by the young children (http://www. dhpe. org/infect/cytomegalo. html retrieved on 05/05/2008). Conclusion This disease is easy to control from the midst of many communities in the world.
Nevertheless, the main need is the addressing of the cleanliness issues of the community. The disease is an opportunistic disease to the people who are already suffering from the disease without testing. Tests that have been done need to be monitored to be able to prevent the fetuses from contracting the disease too.
References
http://www. dhpe. org/infect/cytomegalo. html retrieved on 05/05/2008 http://69. 7. 225. 164/parent/infections/bacterial_viral/cytomegalovirus. html Retrieve on 05/05/2008 http://www. stlukeseye. com/Conditions/CMV. asp Retrieved on 05/05/2008).