The study yielded positive results, and established that the menstrual cycle and the fluctuation in sex steroid hormones are relevant factors in influencing cocaine craving caused by drug cues and stress (Sinha, Fox, Hong, Sofuoglu, Morgan & Bergquist, 2007). Moreover, …
Cimetidine is the most prototypical drug ever to be tested and shown to have exciting antagonistic properties with histamine H2-receptor. After GlaxoSmithKline’s development in about mid 1960s, a number of histamine H2 receptor antagonists have been developed. H2 receptor antagonists …
Histamine binds to the pockets of the alpha helixes of the transmembrane histamine H2 receptor. Within the phopholipid bilayer of the plasma membrane, there is a specific pocket for small lipophillic biogenic amines. Agonists (histamine) and antagonists (cimetidine) bind to …
Cimetidine is a histamine congener which inhibits the binding of histamine competitively to H2 receptors. After its binding to the H2 receptor, cimetidine causes a range of pharmacological responses through the inhibition of secretion of gastric acid by parietal cells …
Different institutions use different procedures in analyzing abuse of drugs. One of these is the Behavior Pharmacology Program that uses operant behavioral procedures where the goal is to determine how drug self-administration is modified both by manipulation of behavioral contingencies …
Are the behaviors we see in adolescents simply a result of “raging hormones”? Certainly that’s not the complete answer, but changes in reproductive and stress hormones can also influence behavior. Hormonal changes during adolescence can also trigger depression during this …
You must first learn about the risk to your mind and body. No drug is without risk, in either the short or long run, although, of course, some drugs, like heroin and alcohol, carry greater risk than others, like aspirin …
There are principles of reinforcement in habit formation in order to understand how many people get so involved with drugs that they cannot let go. These principles are gaining ascendancy as the major theory of addiction to drugs like heroin …
If you find yourself in a social group in which drug-taking is common and approved, the chances are that you will try the drug of fashion that is offered to you – cigarettes, alcohol, pot, et cetera. Accordingly, close to …
There has been much confusion over the concept of addiction, habit, and dependency. Even drug experts have problems with clear definitions. To me, the word are interchangeable because they simply describe repetitious behavior in the presence of a signal for …
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